In-Depth Analysis: CVS Test Procedure, Cost, and Risks (2024)

A Chorionic Villous Sampling (CVS) test is a genetic screening option, performed early in pregnancy, and provides detailed information about your baby’s chromosomes. Unlike Non-Invasive Prenatal Testing (NIPT), which analyses fetal DNA in your blood, CVS directly examines placental tissue for a wider range of conditions. A CVS test is invasive compared to NIPT test. However, if you have concerns about your baby’s genetic health due to advanced maternal age, abnormal screening results, family history, or multiple fetuses, a CVS test may offer valuable insights. Let’s explore what it entails.

Demystifying the Procedure: How is the CVS Test Done?

During a CVS prenatal test, a small sample of placental tissue is collected to analyse your baby’s chromosomes. This CVS test for pregnancy can be performed in two ways:

  • Transabdominal: Ultrasound guidance directs a thin needle through your abdomen to reach the placenta.
  • Transcervical: A thin catheter is inserted through your cervix to access the placenta.

Both methods are typically done between 11-14 weeks of pregnancy and involve minimal discomfort.

Transabdominal vs. Transcervical: Understanding the Two CVS Approaches

There are two main methods for performing a CVS pregnancy test:

1. Transabdominal:

  • Preparation: Depending on the clinic, you may need to fast beforehand and fill your bladder for better ultrasound visualization.
  • Procedure: Using ultrasound guidance, a thin needle is inserted through your abdomen to reach the placenta and collect a tissue sample.
  • Discomfort: You may experience mild cramping during the procedure.
  • Recovery: Rest is recommended after the test, but most women resume normal activities quickly.

2. Transcervical:

  • Preparation: This method typically doesn’t require fasting, but your doctor may advise filling your bladder.
  • Procedure: A thin catheter is inserted through your cervix to reach the placenta and collect tissue.
  • Discomfort: This approach can be slightly more uncomfortable than the transabdominal method, but pain medication is rarely needed.
  • Recovery: Similar to the transabdominal approach, rest is recommended after the procedure.

Precautions to be taken after the CVS test:

  • Watch for signs of infection like fever or foul-smelling discharge.
  • Avoid strenuous activity for a few days.
  • Contact your doctor with any concerns about bleeding, cramping, or unusual symptoms.

Choosing between Transabdominal and Transcervical:

While both methods are generally safe, your doctor will recommend the most suitable approach based on your circ*mstances and health history. Consider discussing any concerns you have about CVS with your doctor to make an informed decision.

When is a CVS Test a Good Option?

Consulting a Fetal medicine clinic can help you determine if a CVS test during pregnancy is right for you. It’s often recommended if you have certain risk factors, like:

  • Advanced Maternal Age: Increased risk of chromosomal abnormalities like Down syndrome.
  • Abnormal Prenatal Screening Tests: Elevated risk is identified in tests like first-trimester screening or quad screening.
  • Family History of Genetic Disorders If you or your partner have a known genetic condition, a CVS test can detect its presence in your baby.
  • Multiple Foetuses For twin pregnancies or higher-order multiples, a CVS test can assess each foetus individually.

Beyond chromosomal abnormalities, CVS microarrays can also detect specific genetic conditions like cystic fibrosis or muscular dystrophy.

Decoding Your Results: What to Expect After a CVS Test

CVS test for pregnancy results typically arrive within 1-2 weeks. The high accuracy of the test provides valuable insight into your baby’s chromosomal makeup and potential genetic conditions. However, in rare cases, the results may be inconclusive. If this occurs, your Fetal medicine specialist might recommend further testing, like amniocentesis, for a more definitive diagnosis.

Weighing the Pros and Cons: Advantages and Risks of the CVS Test

While NIPT testing offers a non-invasive option for early pregnancy screening, the CVS test for pregnancy provides more definitive information. Compared to amniocentesis, done in the second trimester, CVS offers:

  • Earlier results: Receive results within 1-2 weeks, allowing for quicker decision-making.
  • A wider range of detection: Can identify a broader spectrum of genetic conditions beyond common chromosomal abnormalities.

However, it’s crucial to understand the potential risks associated with CVS, similar to amniocentesis:

  • Miscarriage: Slightly increased risk compared to routine pregnancy.
  • Bleeding and infection: Rare, but possible complications.
  • Rh sensitisation: Further monitoring is necessary if the mother is Rh-negative and the baby is Rh-positive.
  • Limb defects: Extremely rare, primarily associated with early CVS procedures.

Remember, these risks are relatively low, but discussing them thoroughly with your healthcare professional is essential before deciding if a CVS test is right for you.

Understanding Costs: Navigating the Financial Aspect of a CVS Test

It’s normal to be uncertain about the CVS test pregnancy cost. The cost of a CVS prenatal test can vary depending on factors like insurance coverage, location, and the specific facility. It’s generally higher than NIPT testing but can offer more comprehensive information. To get a clearer picture of CVS test cost, contacting your healthcare provider for specific estimates and coverage details is recommended.

Bottom Line

The CVS test is a valuable tool for assessing your baby’s chromosomal makeup and potential genetic conditions during pregnancy. While offering earlier results and a wider range of detection compared to some other options, it’s crucial to weigh the potential risks with your healthcare professional.

Ankuran Clinic understands the complexities of pregnancy and provides a supportive environment for informed decision-making. Our team of experienced professionals offers comprehensive consultations, advanced technology, and compassionate care throughout your journey.

In-Depth Analysis: CVS Test Procedure, Cost, and Risks (2024)

FAQs

What are the risks of CVS testing? ›

Some risks of this procedure include:
  • Cramping, bleeding, or leaking of amniotic fluid (water breaking)
  • Infection.
  • Miscarriage.
  • Preterm labor.
  • Limb defects in infants, a higher risk in CVS tests done before 9 weeks. This is rare.

How do I prepare for the CVS test? ›

Preparing for CVS

You will not usually need to do anything special to prepare for CVS. You can eat and drink as normal beforehand. In some cases, you may be asked to avoid going to the toilet for a few hours before having CVS because it's sometimes easier to do the test when your bladder is full.

What is the cost of CVS testing? ›

The cost of Chromosome Analysis, Chorionic Villus Test can be from INR 10,000 to INR 15,000.

Can CVS testing be wrong? ›

How reliable are the results? CVS is estimated to give a definitive result in 99 out of every 100 women having the test. But it cannot test for every condition and it's not always possible to get a conclusive result.

What are the risks and side effects of CVS? ›

Some of the possible side effects, risks and possible complications of CVS include:
  • light-headedness.
  • abdominal discomfort.
  • pains that feel similar to menstrual cramps.
  • haemorrhage.
  • infection.
  • ruptured amniotic sac.
  • miscarriage, estimated at one in 100.

How long does a CVS procedure take? ›

The test itself takes about 10 minutes, although the whole consultation may take about 30 minutes. The CVS procedure is usually described as being uncomfortable rather than painful, although you may experience some cramps that are similar to period pains for a day or two afterwards.

Is CVS more risky than AMNIO? ›

Counselors should discuss the risk for miscarriage attributable to both procedures: the risk from amniocentesis at 15-18 weeks' gestation is approximately 0.25%- 0.50% (1/400-1/200), and the miscarriage risk from CVS is approximately 0.5%-1.0% (1/200-1/100).

What to do after a CVS procedure? ›

If you do experience spotting, use sanitary napkins (not tampons). Do not have sexual intercourse, soak in bath water, or go swimming until your spotting has stopped completely for 3 days. Are there any restrictions after CVS? Avoid strenuous activity for approximately 24 hours after the procedure.

How common is CVS testing? ›

CVS is not routinely offered in pregnancy. It's only offered if there's a high chance your baby could have a genetic or chromosomal condition.

Is CVS testing worth it? ›

What are the benefits of having CVS? The test can tell you if your baby may be born with certain kinds of serious health problems. Many parents are not prepared to care for a baby who is sick or has a birth defect. Information that you get from this test can help you and your partner plan for the future.

Is CVS genetic testing covered by insurance? ›

The cost of a CVS procedure depends on where you get it and whether you have insurance. Many insurance plans cover at least some of the cost of CVS, but check with your insurance company to be sure. If you don't have insurance or your plan doesn't cover the procedure, you'll have to pay for it yourself.

What happens if CVS is positive? ›

If you have a rhesus-negative blood group and the baby has a rhesus-positive blood group, you may produce tiny proteins called antibodies against the baby's blood cells following CVS. These antibodies can assault the baby's red blood cells, causing rhesus disease.

What are the risks of CVS test? ›

CVS can cause miscarriage, which is the loss of a pregnancy in the first 23 weeks. The chance of miscarrying after CVS is thought to be less than 1 in 200 for most pregnancies. The chance is slightly higher at 1 in 100 for multiple pregnancies (such as twins or triplets).

How painful is CVS testing? ›

Chorionic villus sampling is not painful, though you may feel some discomfort. There are two ways healthcare providers perform the test: Transcervical (through the vagin*): Your provider inserts a speculum into your vagin*. This smooth device is shaped like a duck's bill and is also used for Pap tests.

What is the difference between NIPT and CVS test? ›

NIPT is a genetic screening, not a diagnostic test.

Unlike genetic tests that can be done during pregnancy such as amniocentesis or chorionic villus sampling (CVS), NIPT can't diagnose a condition. It only tells us whether there is a chance a condition exists.

What are the chances of miscarriage with CVS test? ›

In pregnancies that underwent CVS, the risk of miscarriage was 1.5% (13/861), compared with 1.2% (476/39 152) in pregnancies that had first-trimester combined screening and did not have an invasive procedure (P = 0.437).

What are the limitations of chorionic villus sampling? ›

CVS does not detect certain birth defects. For example, it can't detect heart problems, cleft lip or palate or spina bifida. An ultrasound when you're around 18 to 20 weeks pregnant checks for most birth defects.

References

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